IGF-1 LR3
61,05 €
- Powerful anabolic effect: muscle hypertrophy and hyperplasia.
- Improved protein synthesis and nitrogen retention.
- Improved glucose utilization and fat oxidation.
- Accelerated injury healing and tissue regeneration.
- Extended half-life that allows for once-daily dosing.
MECHANISM OF ACTION
Long R3 IGF-1 analog: substitution of Arg at position 3 plus a 13-amino acid N-terminal extension. It minimizes affinity for IGF-binding proteins (IGFBP), drastically prolonging the half-life to 20–30 h compared to 12–15 min for native IGF-1. Full activation of the IGF-1 receptor: tyrosine kinase → MAPK, PI3K/Akt → protein synthesis, cell proliferation, and glucose uptake.
KEY BENEFITS
- Powerful anabolic effect: muscle hypertrophy and hyperplasia.
- Improved protein synthesis and nitrogen retention.
- Improved glucose utilization and fat oxidation.
- Accelerated injury healing and tissue regeneration.
- Extended half-life that allows for once-daily dosing.
SIDE EFFECTS AND SAFETY
Risk of hypoglycemia; administer with food. Mandibular or organic growth at supraphysiological doses. Potential stimulation of the IGF-1 receptor pathway in an oncological context. Prohibited by WADA.
RESEARCH AND CLINICAL NOTES
Well-documented potency advantage over native IGF-1, with a half-life 10–100 times longer. Confirmed activation of muscle satellite cells. Ongoing clinical research on anti-aging.
TARGET PROFILE:
Advanced performance optimization programs, sarcopenia programs, and medically supervised injury recovery protocols.
| Weight | ,26 kg |
|---|
Ingredient 1 - cucumber extract
Ingredient 2 - bilberry extract
1 capsule in the morning
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