Tesamorelin
199,95 €
- FDA Approves Treatment to Reduce Visceral Fat Associated with HIV.
- Significant reduction in visceral fat in clinical trials.
- Improvement in lipid profile and metabolic health.
- Preservation of GH’s natural pulsatile physiology.
- Cognitive Benefits: IGF-1 Modulation in Research on Mild Cognitive Impairment.
MECHANISM OF ACTION
A stabilized synthetic analog of GHRH, with a trans-3-hexenoic acid modification that improves metabolic stability. It binds to the GHRH receptor in the anterior pituitary with high affinity, stimulating the pulsatile release of GH. Its pulsatile profile preserves natural feedback. The subsequent increase in IGF-1 mediates the reduction of visceral fat through enhanced lipolysis.
KEY BENEFITS
- FDA Approves Treatment to Reduce Visceral Fat Associated with HIV.
- Significant reduction in visceral fat in clinical trials.
- Improvement in lipid profile and metabolic health.
- Preservation of GH’s natural pulsatile physiology.
- Cognitive Benefits: IGF-1 Modulation in Research on Mild Cognitive Impairment.
SIDE EFFECTS AND SAFETY
The most common side effects are injection-site reactions, fluid retention, joint pain, and glucose intolerance. Monitor HbA1c. Monitoring of IGF-1 is recommended.
RESEARCH AND CLINICAL NOTES
AWARE Trial: Tesamorelin reduced visceral adipose tissue by 15–20% at 26 weeks compared with placebo in HIV-associated lipodystrophy. Approved by the FDA as Egrifta. Off-label use for visceral obesity not associated with HIV is expanding.
TARGET PROFILE:
HIV medicine, metabolic medicine, visceral fat management programs, and anti-aging protocols.
| Weight | ,26 kg |
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