New
NAD+
54,95 €
FOR PRECLINICAL RESEARCH USE ONLY — NOT APPROVED FOR HUMAN USE.
- Optimization of cellular energy and efficiency in ATP production.
- Activation of sirtuins for the epigenetic regulation of longevity.
- Repair of DNA damage through PARP activation.
- Improved mitochondrial biogenesis.
- Cognitive clarity and support for neurological function.
- Applications in research on addiction and depression.
Description
NAD+
Longevity / Energy / Cellular Health
MECHANISM OF ACTION
Universal cellular cofactor in its oxidized form. It accepts electrons in glycolysis and the TCA cycle, forming NADH, and fuels oxidative phosphorylation. It serves as a substrate for sirtuin deacetylases (SIRT1–7), which regulate longevity; PARP, DNA repair enzymes; and CD38/cADPR, involved in calcium signaling. Its levels decrease by 40–50% by middle age.
KEY BENEFITS
- Optimization of cellular energy and efficiency in ATP production.
- Activation of sirtuins for the epigenetic regulation of longevity.
- Repair of DNA damage through PARP activation.
- Improved mitochondrial biogenesis.
- Cognitive clarity and support for neurological function.
- Applications in research on addiction and depression.
SIDE EFFECTS AND SAFETY
IV: flushing, headache, and nausea if infused too quickly; it should be administered by drip over 2–4 hours. SubQ: discomfort at the injection site. Oral forms are largely ineffective; oral precursors such as NMN/NR are preferred.
RESEARCH AND CLINICAL NOTES
Yoshino et al. (NEJM 2021): NMN supplementation increased NAD+ levels and improved muscle insulin sensitivity in postmenopausal women. IV NAD+ is widely used in addiction medicine. Sirtuins have been confirmed as mediators of longevity.
TARGET PROFILE:
Longevity and anti-aging protocols, IV therapy, cognitive performance programs, and addiction recovery medicine.
Additional information
| Weight | ,26 kg |
|---|
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