{"id":38939,"date":"2026-07-16T11:00:06","date_gmt":"2026-07-16T11:00:06","guid":{"rendered":"https:\/\/selmiswiss.com\/?post_type=product&#038;p=38939"},"modified":"2026-07-16T11:17:22","modified_gmt":"2026-07-16T11:17:22","slug":"ara-290-cibinetide","status":"publish","type":"product","link":"https:\/\/selmiswiss.com\/en\/product\/ara-290-cibinetide\/","title":{"rendered":"ARA 290 (Cibinetide)"},"content":{"rendered":"<div class=\"selmi-peptide-sheet\">\n<div class=\"selmi-peptide-header\">\n<div class=\"selmi-peptide-title\">ARA 290 (Cibinetide)<\/div>\n<div class=\"selmi-peptide-category\">Neuroprotection \/ Anti-inflammatory<\/div>\n<\/p><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-top\">\n<section class=\"selmi-peptide-main\">\n<div class=\"selmi-peptide-section\">\n<h3>MECHANISM OF ACTION<\/h3>\n<p>A non-erythropoietic EPO-derived peptide. It selectively activates the innate repair receptor, the IRR\/common \u03b2-receptor complex, without activating the classic EPO receptor homodimer. Downstream, it reduces NF-\u03baB, upregulates the Nrf2 antioxidant response, promotes the bioavailability of nitric oxide, and modulates the regeneration of small-diameter nerve fibers.  <\/p>\n<\/p><\/div>\n<div class=\"selmi-peptide-section\">\n<h3>KEY BENEFITS<\/h3>\n<ul>\n<li>Significant improvement in symptoms of small-fiber neuropathy, including pain and autonomic function.<\/li>\n<li>Anti-inflammatory action without immunosuppression.<\/li>\n<li>Microvascular endothelial protection and improved tissue perfusion.<\/li>\n<li>Neuroprotection in cases of ischemic and diabetic neuropathy.<\/li>\n<li>No hematopoietic effects; suitable for long-term use.<\/li>\n<\/ul><\/div>\n<\/section>\n<aside class=\"selmi-peptide-dosing\">\n<h3>THE RESULTS DESCRIBED WERE OBTAINED BY FOLLOWING THE DOSAGE AND PROTOCOL SET FORTH BELOW<\/h3>\n<h4>4 mg three times a week subcutaneously<\/h4>\n<p><strong>Vial size:<\/strong><br \/>4 mg<\/p>\n<p><strong>Frequency:<\/strong><br \/>3 times a week<\/p>\n<p><strong>IU \/ Dose:<\/strong><br \/>200 IU<\/p>\n<p><strong>Reconstitution:<\/strong><br \/>Reconstitute with 2 mL of bacteriostatic water. 200 IU = 4 mg. <\/p>\n<p><strong>Cycle:<\/strong><br \/>12-week cycles. Efficacy observed starting in week 4 and beyond. <\/p>\n<\/aside><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-info\">\n<section class=\"selmi-peptide-box\">\n<h3>SIDE EFFECTS AND SAFETY<\/h3>\n<p>Well tolerated in clinical trials. Mild reactions at the injection site. No erythropoietic stimulation.  <\/p>\n<\/section>\n<section class=\"selmi-peptide-box selmi-peptide-box-alt\">\n<h3>RESEARCH AND CLINICAL NOTES<\/h3>\n<p>Phase II trial in small-fiber neuropathy associated with sarcoidosis: significant reduction in pain and improvement in corneal nerve density compared with placebo. Improvement in autonomic function demonstrated in cohorts with diabetic neuropathy. <\/p>\n<\/section><\/div>\n<section class=\"selmi-peptide-profile\">\n<h3>TARGET PROFILE:<\/h3>\n<p><em>Protocols for neuropathy, programs for managing diabetic complications, and specialized practices in autoimmune or inflammatory diseases.<\/em><\/p>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"selmi-div-disclaimer\"><span class=\"selmi-disclaimer-text\">FOR PRECLINICAL RESEARCH USE ONLY \u2014 NOT APPROVED FOR HUMAN USE.<\/span><\/div>\n<ul>\n<li>Significant improvement in symptoms of small-fiber neuropathy, including pain and autonomic function.<\/li>\n<li>Anti-inflammatory action without immunosuppression.<\/li>\n<li>Microvascular endothelial protection and improved tissue perfusion.<\/li>\n<li>Neuroprotection in cases of ischemic and diabetic neuropathy.<\/li>\n<li>No hematopoietic effects; suitable for long-term use.<\/li>\n<\/ul>\n","protected":false},"featured_media":38944,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[1113],"product_tag":[1101],"class_list":["post-38939","product","type-product","status-publish","has-post-thumbnail","product_cat-healing-tissue-repair-peptides","product_tag-peptides","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/comments?post=38939"}],"version-history":[{"count":2,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38939\/revisions"}],"predecessor-version":[{"id":38951,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38939\/revisions\/38951"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media\/38944"}],"wp:attachment":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media?parent=38939"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_brand?post=38939"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_cat?post=38939"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_tag?post=38939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}