{"id":38135,"date":"2026-07-08T18:58:29","date_gmt":"2026-07-08T18:58:29","guid":{"rendered":"https:\/\/selmiswiss.com\/?post_type=product&#038;p=38135"},"modified":"2026-07-08T19:06:14","modified_gmt":"2026-07-08T19:06:14","slug":"igf-1-lr3","status":"publish","type":"product","link":"https:\/\/selmiswiss.com\/en\/product\/igf-1-lr3\/","title":{"rendered":"IGF-1 LR3"},"content":{"rendered":"<div class=\"selmi-peptide-sheet\">\n<div class=\"selmi-peptide-header\">\n<div class=\"selmi-peptide-title\">IGF-1 LR3<\/div>\n<div class=\"selmi-peptide-category\">Muscle \/ Growth \/ Recovery<\/div>\n<\/p><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-top\">\n<section class=\"selmi-peptide-main\">\n<div class=\"selmi-peptide-section\">\n<h3>MECHANISM OF ACTION<\/h3>\n<p>Long R3 IGF-1 analog: substitution of Arg at position 3 plus a 13-amino acid N-terminal extension. It minimizes affinity for IGF-binding proteins (IGFBP), drastically prolonging the half-life to 20\u201330 h compared to 12\u201315 min for native IGF-1. Full activation of the IGF-1 receptor: tyrosine kinase \u2192 MAPK, PI3K\/Akt \u2192 protein synthesis, cell proliferation, and glucose uptake.  <\/p>\n<\/p><\/div>\n<div class=\"selmi-peptide-section\">\n<h3>KEY BENEFITS<\/h3>\n<ul>\n<li>Powerful anabolic effect: muscle hypertrophy and hyperplasia.<\/li>\n<li>Improved protein synthesis and nitrogen retention.<\/li>\n<li>Improved glucose utilization and fat oxidation.<\/li>\n<li>Accelerated injury healing and tissue regeneration.<\/li>\n<li>Extended half-life that allows for once-daily dosing.<\/li>\n<\/ul><\/div>\n<\/section>\n<aside class=\"selmi-peptide-dosing\">\n<h3>THE RESULTS DESCRIBED WERE OBTAINED BY FOLLOWING THE DOSAGE AND PROTOCOL SET FORTH BELOW<\/h3>\n<h4>50 mcg\/day subcutaneous \u2014 investigational dose<\/h4>\n<p><strong>Vial size:<\/strong><br \/>1 mg<\/p>\n<p><strong>Frequency:<\/strong><br \/>Once a day<\/p>\n<p><strong>IU \/ Dose:<\/strong><br \/>10 IU<\/p>\n<p><strong>Reconstitution:<\/strong><br \/>Reconstitute with 2 ml of bacteriostatic water. 10 IU = 50 mcg. <\/p>\n<p><strong>Cycle:<\/strong><br \/>4\u20136 weeks. Monitor for possible hypoglycemia. Cycle with 4-week rest periods.  <\/p>\n<\/aside><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-info\">\n<section class=\"selmi-peptide-box\">\n<h3>SIDE EFFECTS AND SAFETY<\/h3>\n<p>Risk of hypoglycemia; administer with food. Mandibular or organic growth at supraphysiological doses. Potential stimulation of the IGF-1 receptor pathway in an oncological context. Prohibited by WADA.   <\/p>\n<\/section>\n<section class=\"selmi-peptide-box selmi-peptide-box-alt\">\n<h3>RESEARCH AND CLINICAL NOTES<\/h3>\n<p>Well-documented potency advantage over native IGF-1, with a half-life 10\u2013100 times longer. Confirmed activation of muscle satellite cells. Ongoing clinical research on anti-aging.  <\/p>\n<\/section><\/div>\n<section class=\"selmi-peptide-profile\">\n<h3>TARGET PROFILE:<\/h3>\n<p><em>Advanced performance optimization programs, sarcopenia programs, and medically supervised injury recovery protocols.<\/em><\/p>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"selmi-div-disclaimer\"><span class=\"selmi-disclaimer-text\">FOR PRECLINICAL RESEARCH USE ONLY \u2014 NOT APPROVED FOR HUMAN USE.<\/span><\/div>\n<ul>\n<li>Powerful anabolic effect: muscle hypertrophy and hyperplasia.<\/li>\n<li>Improved protein synthesis and nitrogen retention.<\/li>\n<li>Improved glucose utilization and fat oxidation.<\/li>\n<li>Accelerated injury healing and tissue regeneration.<\/li>\n<li>Extended half-life that allows for once-daily dosing.<\/li>\n<\/ul>\n","protected":false},"featured_media":38141,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[1113],"product_tag":[1101],"class_list":["post-38135","product","type-product","status-publish","has-post-thumbnail","product_cat-healing-tissue-repair-peptides","product_tag-peptides","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/comments?post=38135"}],"version-history":[{"count":1,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38135\/revisions"}],"predecessor-version":[{"id":38146,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38135\/revisions\/38146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media\/38141"}],"wp:attachment":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media?parent=38135"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_brand?post=38135"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_cat?post=38135"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_tag?post=38135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}