{"id":38096,"date":"2026-07-08T16:16:10","date_gmt":"2026-07-08T16:16:10","guid":{"rendered":"https:\/\/selmiswiss.com\/?post_type=product&#038;p=38096"},"modified":"2026-07-08T16:40:54","modified_gmt":"2026-07-08T16:40:54","slug":"ss-31","status":"publish","type":"product","link":"https:\/\/selmiswiss.com\/en\/product\/ss-31\/","title":{"rendered":"SS-31"},"content":{"rendered":"<div class=\"selmi-peptide-sheet\">\n<div class=\"selmi-peptide-header\">\n<div class=\"selmi-peptide-title\">SS-31 (Elamipretide)<\/div>\n<div class=\"selmi-peptide-category\">Mitochondrial Health \/ Longevity<\/div>\n<\/p><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-top\">\n<section class=\"selmi-peptide-main\">\n<div class=\"selmi-peptide-section\">\n<h3>MECHANISM OF ACTION<\/h3>\n<p>Szeto-Schiller tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2), which selectively targets the inner mitochondrial membrane (IMM) through electrostatic interaction with cardiolipin. It stabilizes the cardiolipin-cytochrome c complex, restores the efficiency of the electron transport chain, reduces mitochondrial ROS production, and preserves the architecture of the mitochondrial cristae. <\/p>\n<\/p><\/div>\n<div class=\"selmi-peptide-section\">\n<h3>KEY BENEFITS<\/h3>\n<ul>\n<li>Restoration of mitochondrial function in aged and diseased tissues.<\/li>\n<li>Improved cardiac function in heart failure.<\/li>\n<li>Renal protection in ischemia-reperfusion injury.<\/li>\n<li>Reduction of neuroinflammation.<\/li>\n<li>Preservation of Muscle Fiber in Aging and Sarcopenia.<\/li>\n<li>FDA Breakthrough Therapy Designation for Barth Syndrome.<\/li>\n<\/ul><\/div>\n<\/section>\n<aside class=\"selmi-peptide-dosing\">\n<h3>THE RESULTS DESCRIBED WERE OBTAINED BY FOLLOWING THE DOSAGE AND PROTOCOL SET FORTH BELOW<\/h3>\n<h4>2 mg\/day subcutaneous<\/h4>\n<p><strong>Vial size:<\/strong><br \/>10 mg<\/p>\n<p><strong>Frequency:<\/strong><br \/>Once a day<\/p>\n<p><strong>IU \/ Dose:<\/strong><br \/>40 IU<\/p>\n<p><strong>Reconstitution:<\/strong><br \/>Reconstitute with 2 mL of bacteriostatic water. 40 IU = 2 mg. <\/p>\n<p><strong>Series:<\/strong><br \/>12-week series. Monitored longevity or cardiac protocol. <\/p>\n<\/aside><\/div>\n<div class=\"selmi-peptide-grid selmi-peptide-grid-info\">\n<section class=\"selmi-peptide-box\">\n<h3>SIDE EFFECTS AND SAFETY<\/h3>\n<p>Reactions at the injection site are the most common. Generally well tolerated in clinical trials. No significant systemic adverse events have been observed.  <\/p>\n<\/section>\n<section class=\"selmi-peptide-box selmi-peptide-box-alt\">\n<h3>RESEARCH AND CLINICAL NOTES<\/h3>\n<p>EMPOWER-HF Trial: SS-31 improved cardiac function in heart failure with preserved ejection fraction. Trials in Barth syndrome: The FDA advisory committee voted 9-4 in favor of its efficacy. Multiple ongoing Phase II\/III trials.  <\/p>\n<\/section><\/div>\n<section class=\"selmi-peptide-profile\">\n<h3>TARGET PROFILE:<\/h3>\n<p><em>Cardiovascular medicine, longevity protocols, and mitochondrial medicine.<\/em><\/p>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div class=\"selmi-div-disclaimer\"><span class=\"selmi-disclaimer-text\">FOR PRECLINICAL RESEARCH USE ONLY \u2014 NOT APPROVED FOR HUMAN USE.<\/span><\/div>\n<ul>\n<li>Restoration of mitochondrial function in aged and diseased tissues.<\/li>\n<li>Improved cardiac function in heart failure.<\/li>\n<li>Renal protection in ischemia-reperfusion injury.<\/li>\n<li>Reduction of neuroinflammation.<\/li>\n<li>Preservation of Muscle Fiber in Aging and Sarcopenia.<\/li>\n<li>FDA Breakthrough Therapy Designation for Barth Syndrome.<\/li>\n<\/ul>\n","protected":false},"featured_media":38102,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[1116],"product_tag":[1101],"class_list":["post-38096","product","type-product","status-publish","has-post-thumbnail","product_cat-longevity-anti-aging-peptides","product_tag-peptides","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38096","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/comments?post=38096"}],"version-history":[{"count":1,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38096\/revisions"}],"predecessor-version":[{"id":38108,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product\/38096\/revisions\/38108"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media\/38102"}],"wp:attachment":[{"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/media?parent=38096"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_brand?post=38096"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_cat?post=38096"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/selmiswiss.com\/en\/wp-json\/wp\/v2\/product_tag?post=38096"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}